Ulusal Romatoloji Dergisi / Journal of Turkish Society for Rheumatology
 
 
p-ISSN: 2651-2653
e-ISSN: 2651-2661
Editor-in-Chief
Haner Direskeneli
2018 Volume 10
 
 
Deomed Yayıncılık
 
 
 
Volume 7, Issue 1, June 2015
Page(s): 10-15
 
Review
Received: July 7, 2015; Accepted: July 14, 2015; Published online: November 25, 2015
doi:10.2399/raed.15.54254; Copyright © 2015 Rheumatology Association of Turkey (TRD).
Giant cell (temporal) arteritis
Mehmet Ali Balcı (E-mail), Ömer Nuri Pamuk
Trakya Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Romatoloji Bilim Dalı, Edirne
Summary
Giant cell (temporal) arteritis (GCA) is a chronic vasculitis which involves large and medium size vessels. History and physical examination hold the most important place for diagnosis of GCA. New-onset headache is observed in at least two-thirds of GCA patients. Visual loss is the most important complication of disease; and its symptoms may develop slowly within a few weeks or months. Sudden visual loss may develop in some cases with rapid progression. Characteristic laboratory findings of GCA are increased sedimentation rate and CRP which is observed in most patients. Magnetic resonance/angiography, conventional angiography, doppler ultrasonography and positron emission tomography can be used for diagnosis of GCA. Temporal artery biopsy must be performed in all patients suspected of having GCA. If there is any suspicion of GCA, steroid therapy should be started immediately. Adding methotrexate to therapy might be useful in GCA patients who are at high risk for steroid side effects or who have developed steroid effects. While TNF blockers were found to be noneffective in refractory GCA patients, promising results were reported with IL-6 inhibitors.
Keywords: Giant cell arteritis, temporal arteritis, vasculitis
 
 
Reklam
 
   
RAED Dergisi / RAED Journal

Türkiye Romatoloji Derneği (TRD) yayın organıdır. Deomed Yayıncılık tarafından yayımlanmaktadır. / Official Publication of the Rheumatology Society of Turkey (TRD). Published by Deomed Publishing. Copyright © 2018, TRD.
Creative Commons License
RAED Dergisi çevrimiçi (online) sürümünde yayımlanan akademik içeriğin kullanım hakları, ilgili içerikte tersi belirtilmediği sürece Deomed Yayıncılık tarafından Creative Commons Attribution-NoCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND3.0) lisansı aracılığıyla bedelsiz sunulmaktadır. / Except where otherwise noted, academic content of this online version of the journal by Deomed Publishing is licensed under the terms of Creative Commons Attribution-NoCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND3.0) License.