p-ISSN: 1301-4021
e-ISSN: 2147-2548
Haner Direskeneli
2018 Volume 10
Deomed Yayıncılık
Volume 9, Issue 1-2, December 2017
Page(s): 6-10
Received: April 17, 2017; Accepted: May 31, 2017; Published online: November 1, 2017
doi:10.2399/raed.17.18291; Copyright © 2017 Rheumatology Association of Turkey (TRD).
Polyarteritis nodosa (PAN): is it a single disease?
Ömer Karadağ (E-mail)
Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Hacettepe University, Ankara, Turkey
Even though PAN was described many years ago, there has been little progress in understanding its cause or component subgroups, in part, due to its rarity. It has a wide range of disease onset age and clinical symptoms and signs in addition to major differences between subgroups in terms of relapses, survival rates and recommended treatment strategies. Most of PAN subphenotypes demonstrate different clinical courses and therefore may be different diseases rather than a spectrum of the same disease. There is a need to better understand the subphenotypes of PAN in order to research into epidemiologic and aetiologic associations, necessary to develop improved therapies.
Keywords: Polyarteritis nodosa (PAN), vasculitis, hepatitis B (HBV)-associated PAN, adenosine deaminase-2 deficiency, familial Mediterranean fever (FMF), cutaneous PAN
RAED Dergisi / RAED Journal

Türkiye Romatoloji Derneği (TRD) yayın organıdır. Deomed Yayıncılık tarafından yayımlanmaktadır. / Official Publication of the Rheumatology Society of Turkey (TRD). Published by Deomed Publishing. Copyright © 2018, TRD.
Creative Commons License
RAED Dergisi çevrimiçi (online) sürümünde yayımlanan akademik içeriğin kullanım hakları, ilgili içerikte tersi belirtilmediği sürece Deomed Yayıncılık tarafından Creative Commons Attribution-NoCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND3.0) lisansı aracılığıyla bedelsiz sunulmaktadır. / Except where otherwise noted, academic content of this online version of the journal by Deomed Publishing is licensed under the terms of Creative Commons Attribution-NoCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND3.0) License.