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The association between disease activity and depression, anxiety, and quality of life in patients with ankylosing spondylitis
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Original Article
VOLUME: 13 ISSUE: 3
P: 94-99
December 2021

The association between disease activity and depression, anxiety, and quality of life in patients with ankylosing spondylitis

J Turk Soc Rheumatol 2021;13(3):94-99
DOI: 10.4274/raed.galenos.2021.19480
Sema Kaynak Güvener 1
Orhan Güvener 1
Pınar Müge Sarıkaya 2
Asena Ayça Özdemir 3
Günşah Şahin 1
1. Mersin Üniversitesi Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Mersin, Türkiye
2. Mersin Şehir Eğitim ve Araştırma Hastanesi, Fiziksel Tıp ve Rehabilitasyon Kliniği, Mersin, Türkiye
3. Mersin Üniversitesi Tıp Fakültesi, Biyoistatistik Anabilim Dalı, Mersin, Türkiye
No information available.
No information available
Received Date: 18.02.2021
Accepted Date: 11.10.2021
Publish Date: 22.12.2021
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ABSTRACT

Conclusion:

In our study, it was concluded that the quality of life of AS patients with active disease decreased, the rates of anxiety and depression in AS patients were higher than those of healthy individuals, and it negatively affected the quality of life. Therefore, we think that psychiatric evaluation should be part of the management of AS patients and supporting mental health will positively affect quality of life and prognosis in AS patients.

Results:

The age and gender distribution were similar between the groups. When the two groups were compared, the patient group had higher mean scores for depression and anxiety (for AS patients 14.89±10.23, 11.59±10.59; for healthy group 3.81±5.49, 2.04±3.08). AS patients with low BASDAI scores had lower BDI, BAI and ASQoL scores compared to those with high scores. While there was no significant difference in the HLA-B27 positive AS group in terms of BDI and ASQoL scores, BAI score was significantly higher in the HLA-B27 positive group (p<0.001). There was a positive relationship between the ASQoL, BASDAI and BASFI scores (p=0.005).

Methods:

Hundred and ten subjects, including 57 patients with AS and 53 healthy controls, participated in the study. Depression and anxiety levels of all participants were evaluated with the BECK Depression Inventory (BDI) and the BECK Anxiety Inventory (BAI). Disease activity was evaluated with Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), functional status with Bath Ankylosing Spondylitis Functional Index (BASFI), and quality of life with Ankylosing Spondylitis Quality of Life Questionnaire (ASQoL).

Objective:

The objective of this study is to investigate the relationship between disease activity and depression, anxiety and quality of life in ankylosing spondylitis (AS).

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