Clinical approach to resistant inflammatory myositis: rheumatology perspective
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Review
P: 57-60
December 2011

Clinical approach to resistant inflammatory myositis: rheumatology perspective

J Turk Soc Rheumatol 2011;3(3):57-60
1. İstanbul Üniversitesi İstanbul Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Romatoloji Bilim Dalı, İstanbul
No information available.
No information available
Received Date: 25.04.2011
Accepted Date: 30.08.2011
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ABSTRACT

Resistant idiopathic inflammatory myositis (IIM) defines IIM with clinical and/or laboratory findings not responding to immunosuppressive treatment. In the presence of the lack of response to standard treatment modalities, disease related damage, underlying malignancy, undertreatment should be considered besides resistant myositis. Different types of non-inflammatory myopathies that mimics IIM also need to be ruled out in resistant myositis cases. Detailed history, pyhsical examination and laboratory work-up should carefully be re-evaluted. Muscle biopsy performed at initial diagnosis has to be scrutinized in terms of prerequisites of sampling and adequate pathologic evaluation in resistant cases. Taking a new biopsy sample might be needed to exclude the myopathies that mimics IIM.

Keywords:
Myositis, dermatimyositis, polymyositis, inflammatory myopathy, resistance to treatment